ODM-201 1297538-32-9 CAS NO.1297538-32-9

Classification: Pharmaceutical

Cas NO.: 1297538-32-9

Name: ODM-201

Molecular Formula: C19H19ClN6O2

Boiling Point: 719.5±60.0

Refractive index:1.681

Flash Point: 388.9±32.9 °C

Purity: 99%

usage: R&D, intermediates.

Brand Name: Darolutamide

EINECS: 829-313-8

Aliase: Darolutamide

Purity: 99%

Appearance:a white or almost white crystalline powder

Brand: Darolutamide

Package: 25kg drum

ODM-201 is a novel androgen receptor (AR) inhibit designed to inhibit the growth of prostate cancer cells through binding to the AR to inhibit the testosterone-induced AR nuclear translocation. It is particularly used in patients with progressive metastatic castration-resistant prostate cancer. It is effective in inhibiting the activity of some mutant ARs emerging during antiandrogen therapies, including the F876L mutation version which is resistant to enzalutamide and ARN-509 (the second-generation antiandrogens).Therefore, it has potential to overcome the resistance issue occurring upon AR-targeted therapies.